Home Press Release Global Cell-based Assays Market Grows Steadily at a CAGR of 8.76%

Global Cell-based Assays Market Grows Steadily at a CAGR of 8.76%

Introduction

The global cell-based assay market is experiencing significant growth due to the surging prevalence of chronic illnesses like cancer, diabetes, and cardiovascular diseases. These conditions necessitate advanced therapeutic solutions, thereby driving the demand for reliable in vitro testing methods capable of accurately assessing cellular responses.

In addition, heightened investments in life sciences research by governments and academic institutions—through grants and funding initiatives—are fostering the development of innovative cell-based assay technologies. The growing emphasis on biologics and biosimilars further contributes to market expansion, as these treatments require precise cellular platforms to evaluate their safety, potency, and effectiveness.

Moreover, the rise of contract research organizations (CROs) offering specialized cell-based assay services is enhancing the availability of advanced testing solutions, particularly for small and medium-sized pharmaceutical firms. Together, these trends are fueling the widespread integration of cell-based assays in drug discovery, toxicology assessments, and clinical research.

Market Dynamics

Expanding drug discovery and development efforts drive the global market

The growing momentum in global pharmaceutical and biotech research is fueling the demand for cell-based assays. These assays provide dynamic, functional insights into how cells respond to compounds, making them essential tools for drug screening, toxicity evaluation, and mechanism-of-action analysis. Pharmaceutical firms are increasingly adopting cell-based assays to enhance early-stage drug candidate identification, which helps minimize late-stage failures and cut development expenses.

  • Notably, in April 2025, the FDA introduced a pioneering pilot program that permits the use of alternative testing methods—such as human cell-based assays and organs-on-chips—in place of traditional animal testing for antibody drugs. This initiative aims to streamline drug development and boost reliability in preclinical testing.

Moreover, the global rise in chronic and infectious diseases underscores the urgent need for swift and effective therapeutic development, reinforcing the importance of advanced, scalable cell-based assay technologies in the current drug discovery landscape.

Emergence of label-free real-time technologies creates tremendous opportunities

The increasing adoption of label-free, real-time technologies in the cell-based assays market is unlocking new avenues for innovation and enhancing the reliability of research data. Unlike conventional assays that depend on fluorescent or colorimetric labels—which can disrupt natural cellular functions—label-free methods enable continuous, non-invasive observation of cellular activities such as proliferation, morphology changes, and cytotoxic responses. These technologies help minimize variability and improve the consistency of results across both research and industrial settings.

  • An example is Nanolive’s Smart Mitochondrial Assay LIVE, introduced in March 2025. This pioneering assay uses artificial intelligence to track mitochondrial behavior—including fission, fusion, and mitophagy—in live cells without the need for dyes. It delivers precise, real-time insights for applications like drug screening, toxicology studies, and disease modeling, ensuring greater reproducibility and operational efficiency.

As the demand grows for more accurate and biologically relevant testing methods, label-free technologies are set to transform the landscape of cell-based assays.

Regional Analysis

North America holds a dominant share in the global cell-based assays market due to strong pharmaceutical R&D investments and advanced healthcare infrastructure. The U.S., in particular, leads the region, driven by extensive drug discovery activities and the presence of major players like Thermo Fisher Scientific, Danaher Corporation, and Bio-Rad Laboratories. For instance, in 2024, Thermo Fisher expanded its portfolio with high-content screening platforms tailored for oncology drug testing.

Additionally, the surging focus on personalized medicine and immunotherapy—such as CAR-T cell research—has increased the use of cell-based assays in clinical research. Canada is also making strides, with institutions like the University of Toronto integrating 3D cell culture assays in toxicology and disease modeling. Moreover, regulatory support from agencies like the FDA, which encourages alternatives to animal testing, continues to promote assay innovation across North America.

Key Highlights

  • The global cell-based assays market size was valued at USD 17.25 billion in 2024 and is estimated to grow from USD 18.76 billion in 2025 to reach USD 36.73 billion by 2033, growing at a CAGR of 8.76% during the forecast period (2025–2033).
  • By products & services, the market includes reagents, assay kits, microplates, instruments & software, and cell lines. The assay kits segment held a dominant market share.
  • By technology, the market is segmented into flow cytometry, high throughput screening (HTS), label-free detection, and automated handling systems.
  • By application, the market is divided into drug discovery, basic research, and others. The drug discovery segment held the largest market share.
  • By end-user, the market comprises pharmaceutical & biotechnology companies, academic & research institutions, contract research organizations (CROs), hospitals and diagnostic laboratories, and others. The pharmaceutical & biotechnology companies segment dominated the market.
  • North America is the highest shareholder in the global market.

Competitive Players

  1. Thermo Fisher Scientific Inc.
  2. Merck KGaA
  3. Danaher Corporation
  4. Becton
  5. Dickinson and Company
  6. PerkinElmer Inc.
  7. Charles River Laboratories International Inc.
  8. Cell Signaling Technology Inc.
  9. Lonza Group Ltd.
  10. Bio-Rad Laboratories Inc.
  11. Promega Corporation
  12. Others

Recent Developments

  • In May 2025, INDIGO Biosciences expanded its reporter cell‑line portfolio by introducing stable reporter cell lines that complement its existing assay kits. This enhancement enables researchers to streamline workflows in high‑throughput drug discovery and toxicology studies, offering faster, reproducible data from ready‑to‑use cellular models.

Segmentation

  1. By Products & Services
    1. Reagents
    2. Assay Kits
      1. Cell Growth Assays
      2. Reporter Gene Assays
      3. Cell Death Assays
      4. Second Messenger Assays
    3. Microplates
    4. Probes & Labels
    5. Instruments & Software
    6. Cell Lines
      1. Primary Cell Lines
      2. Stem Cell Lines
      3. Immortalized Cell Lines
  2. By Technology
    1. Flow Cytometry
    2. High Throughput Screening (HTS)
    3. Label-Free Detection
    4. Automated Handling Systems
  3. By Application
    1. Drug Discovery
    2. Basic Research
    3. Others
  4. By End-User
    1. Pharmaceutical & Biotechnology Companies
    2. Academic & Research Institutions
    3. Contract Research Organizations (CROs)
    4. Hospitals and Diagnostic Laboratories
    5. Others
  5. By Regions
    1. North America
    2. Europe
    3. Asia-Pacific
    4. Latin America
    5. The Middle East and Africa

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